Description
PREDNISOLONE TABLETS 5 MG POM.
COMPOSITION: Each Tablet contains 5mg prednisolone
Petsow prednisolone is presented as a White circular tablet with a break line across the middle of one side of the tablet marked PRED-5
INDICATIONS: Petsow Prednisolone is a corticosteroid with mainly glucocorticoid activity. It is used in suppression of inflammatory and allergic disorders.
CONTRA-INDICATIONS: Absolute active or cured turberculosis, ophthalmic herpes simplex, peptic ulcer, osteoporosis, diabetes, hypertension, renal insufficiency. Cushing’s syndrome, healing wounds, myasthenia gravis, acute and chronic infections.
SIDE EFFECTS:
Relative adrenocortical insufficiency, increased catabolism of protein with negative nitrogen balance, disorders of electrolyte balance, disorders in metabolism of glucose with aggravation of diabetes, osteoporosis, spontaneous fractures of bones, aseptic necrosis of the hip, myopathies, activation and aggravation of peptic ulcer, abnormal euphoria, increased in appetite and body weight, tissue atrophy, hypopigmentation of skin, post injection swelling and reactions similar to shock.
ADVERSE REACTIONS:
Concurrent administration of barbiturates, carbamazepine, phenytoin, primidone, or rifampicin may enhance the metabolism and reduce the effects of corticosteroids. Concurrent administration of corticosteroids with potassium-depleting diuretics, such as thiazides or frusemide, may cause excessive potassium loss. There may be an increased incidence of gastro-intestinal bleeding and ulceration when corticosteroids are given with NSAIDs. Response to anticoagulant may be altered by corticosteroids and requirements of antidiabetic agents and antihypertensives may be increased. Corticosteroids may decrease serum concentrations of salicylates and may decrease the effect of antimuscarinics in myasthenia gravis.
ROUTE AND CONDITIONS OF ADMINISTRATION:
1. Route of Administration: Oral
2. Condition of administration: 5 to 60 mg daily in divided doses as a single daily dose after breakfast or as a double dose on alternate day
ANTIDOTE IN THE EVENT OF OVERDOSAGE:
In the event of over dosage due to use in excess of normal physiological requirements, treatment should be symptomatic and where possible the dosage is reduced or the drug slowly withdrawn.
STORAGE/WARNINGS: It should be stored in airtight containers, away from direct sources of light and moisture at a temperature below 30˚C and KEEP OUT OF THE REACH OF CHILDREN.
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